Titanium dioxide is a POSSIBLE CANCER HAZARD. Before handling, it is very important that engineering controls are operating and that protective equipment requirements are being followed. People working with this chemical should be properly trained regarding its hazards and its safe use. Maintenance and emergency personnel should be advised of potential hazards.

When working with fine or ultrafine powders, immediately report leaks, spills or ventilation failures. Consider using closed handling systems or wet processes for large-scale operations involving fine or ultrafine powders. Avoid generating dusts. Prevent the release of dusts into the workplace air. Use in the smallest possible amounts in a well ventilated area, separate from the storage area.

Use the proper tools to open containers. Ripping open a container can cause an uneven tear, thus making spills more likely. Stand upwind of all opening, dispensing and mixing operations. Keep containers closed when not in use.

Good housekeeping is important to prevent accumulations of dust. Dry sweeping is not recommended. Pre-wet the material or use a vacuum equipped with high efficiency filter(s).

Do not use with incompatible materials such as magnesium, lithium or zinc. See Incompatibilities - Materials to Avoid section for more information.

Follow handling precautions on Material Safety Data Sheet. Have suitable emergency equipment for spills and leaks readily available. Maintain handling equipment. Comply with applicable regulations.